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Questions and answers

The questions people ask most about HELIXAFE and Cancer Driver Interception, answered in plain words.

These answers come from the HELIXAFE guide to Cancer Driver Interception. If your question is not here, write to our biologists: we are building the questions people actually ask into what we publish next.

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Educational content. Not a substitute for medical advice. HELIXAFE does not diagnose, treat, predict or prevent disease and does not replace recommended cancer screenings.

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Questions

Questions about this topic

What is HELIXAFE?
A physician-guided, blood-based program for Cancer Driver Interception, powered by Bioscience Institute. It reads acquired changes across more than 50 tumor suppressor genes and follows them over time.
What is Cancer Driver Interception?
Following the changes that build in the years before there is cancer to find, to see whether they hold steady or progress, and to give you the chance to act while they can still be acted on.
What is a Cancer Driver Condition?
A progressive pattern across repeated HELIXAFE tests. One test does not establish it. It is not cancer, and it does not mean you have cancer.
Can a blood test follow cancer risk over time?
HELIXAFE is built to do something close to that, carefully defined: it does not estimate a risk score. It reads acquired changes in more than 50 tumor suppressor genes at a first test (your reference) and shows at each following test whether those changes hold steady, build or build faster. Your physician reads that direction alongside the rest of your health.
Why does HELIXAFE read tumor suppressor genes?
Think of them as your cells’ braking system. They repair damaged DNA, control cell division and stop damaged cells from carrying on. HELIXAFE follows the changes affecting those brakes.
What are somatic, or acquired, changes?
Changes in your DNA that happen during your life, as damage is repaired imperfectly over the years. They are different from the hereditary variants your parents passed on to you.
Is HELIXAFE hereditary cancer testing?
No. Hereditary testing reads variants inherited from your parents. HELIXAFE reads changes you acquired during your life. It is not a BRCA test.
Is HELIXAFE a cancer detection test?
No. Detection looks for evidence that cancer is already present. HELIXAFE reads the years before there is cancer to find.
What does my first test do?
It tells you where you stand today, and it becomes the reference every future test is read against.
Why test again?
Because the direction is the information. Repeated tests show whether the changes hold steady, build, or build faster.
When do I test again?
Your physician decides, based on your previous results and the program protocol.
What happens if a Cancer Driver Condition is developing?
It does not mean you have cancer. Your physician reads the pattern alongside the rest of your health, decides how closely to watch it, and decides whether further evaluation is appropriate.
What if my results stay stable?
Stable means the changes HELIXAFE follows are not progressing. You keep following them. Stable results do not mean you cannot develop cancer, so keep every screening recommended for you.
What does my physician do?
They put your results in the context of your health, decide how closely to follow them, and decide when further evaluation or specialist care is appropriate.
Does HELIXAFE replace cancer screening?
No. They do different jobs. Keep every cancer screening and oncology follow-up recommended for you.
Where is the laboratory?
The sequencing and the analysis are done in the Bioscience Institute laboratory in Boston, Massachusetts. The blood sample is drawn by a nurse at your home.
Who can use HELIXAFE?
Adults 18 and over, subject to physician review and prescription. Availability and regulatory classification vary by jurisdiction.
When can I start?
When HELIXAFE opens in the United States. Join the waitlist at helixafe.bioinst.com and you will hear first.

Cancer Driver Interception

Read the years before a diagnosis.

A physician-guided blood program that follows the changes across more than 50 tumor suppressor genes over time, alongside every screening recommended for you.

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